sclerodermie : rapport de quatre cas

four cases of sclerodermia have been reported durintwo months. sclerodermia which seems to he hardness of the skin is actually a general affection that first appears on the skin and has various types: edematous, sclerema for children, and then the forms of patches or drops or bands or annulars. it is sor t of connective tissue affection and is chiefly observed in women and as the reason for it, is thought to be due to the acute infections and chronic toxics in theory dysendocryno- sympathic that eventually is caused by nervous- mental disturbances and shocks. three of the pa t ients were adults and one of them was a 60 years old man. clinical symptoms were common in all three persons and as a usual it began from the fingers and then it appeared in the face, but in the man it was different and the disease began first from the chest and abdomen and buttucks parts, and although the duration of the illness was more than few months it had not yet affected the limbs. after sometime it affects the muscles and bones and in a few years it expands so that causes a general weakness and eventually results in death. the treatment is tern porary and differs comparatively in different cases. vitamin e given with large dosage, vitamin d2 to keep calcium from running. bismuth, penicilline with large dosage and tetracycline given continuously, and at last cortisone and a.c. which have temporary and rapid results